Symbol
Name
ID

Ttc7
tetratricopeptide repeat domain 7
MGI:1920999

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes

Decreased circulating antibody level

Agammaglobulinemia

Autoimmune hemolytic anemia

Lymphopenia

Leukocytosis

Impaired lymphocyte transformation with phytohemagglutinin

Hypoplasia of the thymus

Enterocolitis

Interface hepatitis

Psoriasiform dermatitis

Autoimmunity

Severe combined immunodeficiency

Recurrent respiratory infections

Disease(s) Associated with TTC7A

multiple intestinal atresia

Mouse Phenotypes

stomach inflammation

thymus cortex hypoplasia

decreased thymus weight

small thymus

enlarged spleen

increased spleen weight

increased dendritic epidermal T cell number

increased leukocyte cell number

increased Langerhans cell number

increased spleen red pulp amount

decreased spleen white pulp amount

liver inflammation

Availability

Mouse Genotype

Ttc7^fsn-Jic/Ttc7^fsn-Jic

Ttc7^fsn/Ttc7^fsn

Ttc7^hea/Ttc7^hea

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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